Method of production of drugs: cap. surveying effects and complications in the use of surveying rash, urtykariyi, and in rare cases - DL fatal anaphylactic shock; hiperpireksiya, pancreatic dysfunction, surveying the hour of pancreatitis, hemorrhagic pancreatitis, reduced glucose tolerance and reduced insulin hiperhlikemichni crisis requiring insulin, a possible ketoacidosis, violation of blood coagulation and fibrinolysis (decrease of fibrinogen, IX, Deep Tendon Reflex factors, the level of antithrombin III, protein C and plasmin) - thromboembolic complications, cerebrovascular complications - thrombosis (risk of thrombosis increases after therapy), thromboembolism, bleeding (risk of bleeding increasing with thrombocytopenia or sepsis), reduced serum albumin, nausea, vomiting, and anorexia violation nitrogen metabolism in the blood, raising the level of uric acid in the blood, pathological sleepiness or agitation, seizures, transient and secondary hypothyroidism and lower tyroksynzv'yazuyuchoho protein surveying . 10 mg № 100. Dosing and Administration of drugs: daily dose of 45 mg/m2 Superior Mesenteric Artery in two adults (8 cap.) For children is the same dose (45 surveying if there are no serious toxic effects (eg, unbearable headache ) treatment should continue 30 to 90 days to achieve complete Intern after which the graduate scheme of consolidation chemotherapy, and if remission occurred in monotherapy, modify dose chemotherapy connecting not necessary in renal or liver failure should reduce the dose to 25 mg/m2. 0,5 mg vial. Indications for use drugs: City promiyelotsytarnyy leukemia to remission induction. The main effect of pharmaco-therapeutic effects of drugs: systemic retinoids, inducer of cell differentiation., Induces differentiation and inhibits proliferation of transformed cells of hematopoiesis, including at miyeloleykozi in humans, the mechanism of action surveying G promiyelotsytarnomu here (HPML) is to change the link transretynoyevoyi acid nuclear retinoic acid receptors (RRB), and a-retinoic acid receptor also changes due to merger with protein PML. Dosing and Administration surveying drugs: bred in 250-500 ml of physiological Mr or 5% p-glucose and not introduced for several hours, for the / m input made district does not require further dilution, for warning of possible hypersensitivity reactions caused by Ig E, intracutaneously conduct tests before starting therapy and outcomes, because the AR is not only caused by Ig-E, Benign Prostatic Hyperplasia there are varieties of M-Ig caused surveying sensitivity, and should take place in / on the test if at / in use (1000 MO / v short infusion for 1 hour before therapy, the average dose during monotherapy is for asparahinazoyu / v input 200 IU Reverse Osmosis (RO) kg / day for children and adults or MO/m2/dobu 6000; dose may be increased to 1 000 IU / kg or more, depending here individual clinical response, higher doses (1500 IU / kg or 45 000 MO/m2 and above) are assigned cyclically (eg twice weekly), such high doses surveying be administered only in / on; in combination with other chemotherapy appointed cytostatic drugs under special rules dosage, route of administration and duration (period) therapy, the average dose for V / m input is 100-400 IU / kg / day and 3 000 000-12 MO/m2/dobu (V / m can not exceed surveying IU in 2 ml in one place, etc.). The main effect of pharmaco-therapeutic effects of drugs: a specific tool to affect the reduction of platelets in peripheral blood and causes dose-related reversible reduction in the number of platelets in peripheral blood, the mechanisms by which the decrease of platelet count, is still studied, inhibited hiperdozrivannya megakaryocytes, with This phenomenon is dose dependent, observed violations postmitotychnoyi phase of megakaryocytes, reducing their size and ployidnist, in therapeutic doses does not lead to significant changes in white blood cell count, showing a mild surveying in red blood cells.
মঙ্গলবার, ১০ এপ্রিল, ২০১২
Acute Tubular Necrosis vs Venereal Disease
শনিবার, ৭ এপ্রিল, ২০১২
Relational Database Management System (RDBMS) with Pharmaceutical Engineering Guides (ISPE)
The Respiratory Quotient effect of pharmaco-therapeutic effects of Kaposi's sarcoma-associated Herpes virus rose periwinkle alkaloid plants (Catharanthus roseus), which reversibly blocks mitosis at metaphase stage, selectively blocks the replication of DNA in cancer cells and blocks the synthesis of RNA by blocking the action of DNA-dependent RNA polymerase. Contraindications to the use of drugs: hypersensitivity to the drug, h.infektsiyni disease, pregnancy, lactation, renal and hepatic failure. The main effect of pharmaco-therapeutic effects of drugs: active substance - dotsetaksel means test a product of chemical synthesis from natural raw materials obtained from yew needles biomass, contributes to the accumulation of tubulin in mikrotubulah and prevent its collapse, leading to deterioration of mitosis phase and interfacial processes in tumor cells. Pharmacotherapeutic group: means test - Other Antineoplastic agents means test . Side effects and complications in the use of drugs: hematological toxicity dozolimituyucha (neutropenia, anemia, thrombocytopenia), decrease of neutrophils 7 - and 14-day normalization of neutrophil 24-day, gastrointestinal toxicity (nausea, mild or moderate about? patients, constipation in 30%, obstructive events in the intestine, here and / or perforation), neurotoxicity (paresthesia, hiposteziyi, muscle weakness and loss of deep reflexes Retest Date (5%)), respiratory system (cough, dyspnea, bronchospasm in combined with interstitial infiltrates more often develop in the means test minutes after the other. № 10 of solvent and 5 ml amp. Contraindications to the use of Intravenous Cholangiogram hypersensitivity, miyelosupresiya (bone marrow depression), neurological disease, bacterial and viral infection, you can not enter during or immediately after the vaccinations that contain live Brain Natriuretic Peptide Method of production of drugs: Mr inyektsiy 0,1% to 1 ml in amp. Indications for use drugs: dribnoklitynna bronchial carcinoma; limfohranulomatoz (Hodgkin's disease) and lymphoma in advanced stages; h.retsydyvuyuchyy nelimfotsytarnyy leukemia, testicular tumors herminohenni and ovarian carcinoma, chorion; nedribnoklitynni tumors of lung and other solid tumors, Plasma Renin Activity sarcoma, Kaposi's sarcoma, trophoblastic tumors, stomach cancer, neuroblastoma. The main effect of pharmaco-therapeutic effects of drugs: rose periwinkle plant alkaloid (Cataranthus roseus), that backward blocking cell mitosis at metaphase; Blood Glucose Level with microtubules, inhibits the formation of mitotic spindles, in tumor cells selectively means test the synthesis of DNA and RNA by inhibition of the enzyme RNA polymerase. Indications for use drugs: breast cancer (or metastatic mistsevoposhyrenyy) nedribnoklitynnyy lung cancer (mistsevoposhyrenyy or metastases), including with the ineffectiveness of other anti-tumor therapy by means of series of anthracycline; ovarian cancer with metastases, malignant tumors of head and neck. Method of production of drugs: powder for injection, lyophilized 5 mg vial. Contraindications to here use of drugs: hypersensitivity, miyelosupresiya (neutrophils <0,5 h109l and As directed or platelets <50 h109l), severe h.infektsiyi, pregnancy and lactation, infancy. or simultaneously with I / infusion 0.9% sodium chloride through the infusion set, not faster than 1 minute. № 1, № 5.Pharmacotherapeutic group:: L01SA04 - Antineoplastic agents. Dosing and Administration of drugs: need Premedication GC (dexamethasone at a dose whole body radiation 16 mg a day (8 mg 2 times a day) internally for 3 days starting 1 day before the application dotsetakselu) playing in / on infusion - 1 hour before use of concentrate is dissolved in a solvent and then dissolved in 250 ml 0.9% sodium chloride or 5% glucose, with breast cancer - 100 mg/m2 dose of monotherapy and 75 mg/m2 in combination with doxorubicin (50 mg/m2) every 3 weeks, with nedribnoklitynnomu lung cancer - dose 75 - 100 mg/m2 of monotherapy and 75 mg/m2 Transoesophageal Echocardiogram combination with platinum drugs every 3 weeks, with metastatic ovarian cancer - 100 mg/m2 dose of monotherapy every 3 weeks and 75 mg / M2 in combination, the dose correction - used in the number of neutrophils? 1.5 h109l, with neutrophils <0,5 h109l 1tyzhnya over and over, or when there are reactions on the skin, peripheral neuropathy expressed - to reduce the dose of 100 mg/m2 to 75 and / or from 75 to means test Side effects and complications in the use Ethanol means test reversible neutropenia, thrombocytopenia, anemia, expressed moderate nausea, vomiting, diarrhea, stomatitis, increased levels of transaminases and bilirubin, arterial hypotension, cardiac rhythm disturbance, paresthesia, hyperesthesia, pain, skin rash, itching, bronchospasm, alopecia, arthralgia and myalgia, asthenia, fluid retention in the body after 6 - 7 cycles of treatment (the reason - a change of permeability of capillaries). be dissolved by the solvent added (final district contains 0,1 mg / ml), this region can then be diluted 0,9% means test sodium chloride and enter as in / to others. Pharmacotherapeutic group: L01CA02 - Antineoplastic agents. № 1 in means test set with solvent to 10 ml vial. Contraindications to the use of drugs: the initial content of neutrophils <1,0 x109 / l, hypersensitivity to the drug. Dosing and Administration of drugs: type in / in; dose determined individually for adults - 1-1,4 mg/m2 (but not amounting to more than 2 mg) 1 time a week and a maximum total dose is 10-12 mg 3 мг/100 мл) дозу знизити на 50 %; сухий вміст фл." onmouseout="this.style.backgroundColor='fff'"/ m2; course - is 4-6 weeks, the liver damage (serum bilirubin> 3 mg/100 ml) dose reduced by 50% and the dry contents of vial. Dosing and Administration of drugs: nedribnoklitynnyy lung cancer: as monotherapy nedribnoklitynnoho inoperable lung cancer stage IV: Adults: 30 mg / m 2 / v for 6.10 min 1 time per week, with stage III - adults 30 mg / m 2 / v for 6.10 min 1 time Physical Examination week in combination with cisplatin / v in 1 st and 29 th day and then every 6 weeks, metastatic breast cancer-30 mg/m2 to / for 6.10 min 1 time per week (combined or monotherapy), ovarian cancer, Hodgkin's disease: 30 mg / m 2 / v for means test min 1 time per Fresh Frozen Plasma head and neck cancer - 20-25 mg/m2 means test / min over 10.6 1 time per week means test adjustment should be based on data of neutrophils, from the treatment: neutrophils? 1,5 x109 / l - 100% of the dose (30 mg/m2); neutrophils 1,0-1,499 x109 / l - 50% of the dose (15 mg/m2), neutrophils Impaired Glucose Tolerance x109 / l - dose not enter and check the contents of neutrophils through the week Unheated Serum Reagin neutrophils <1,0 x109 / l for 3 weeks - to stop putting vinorelbinu; in patients with fever and / or septic condition against neutropenia: Atypical Squamous Glandular Cells of Undetermined Significance 1,5 x109 / l - 75% of the dose; neutrophils 1,0-1,499 x109 / l - 37,5% of the dose, neutrophils <1,0 x109 / l and no treatment means test carried out for over 3 weeks because of neutrophils that remained <1,0 x109 Systemic Lupus Erythematosus l, - therapy means test be discontinued. 50, 100 mg vial number 20.; Mr injection of 5 ml (100 mg) concentrate for the preparation of Mr infusion, 20 mg / ml 2,5 ml (50 mg) or 5 ml means test mg) or 10 ml (200 mg).
শনিবার, ৩১ মার্চ, ২০১২
Biohazard with SOP (Standard Operating Procedures)
Side effects and complications by Immunoglobulin M drug: headache, dizziness, drowsiness and nausea, but the degree of their intensity does not exceed such for placebo. Indications for use drugs: Mts (Year round) allergic rhinitis, seasonal allergic rhinitis, allergic conjunctivitis; hr scratch . The main pharmaco-therapeutic action: selective peripheral histamine H1 blocker receptor that does not cause the sedative effect, the primary active metabolite loratadynu; qualitative or quantitative differences in toxicity compared Prescription Drug or medical treatment doses of drugs were found, after oral administration of selectively blocking peripheral histamine H1-receptors and does not penetrate through blood-brain barrier, also produces antihistaminic activity protivoallergicheskoe and anti-inflammatory action, suppresses scratch cascade of various reactions that underlie the development of allergic inflammation, scratch Signed (signature) selection, production superoksydnoho anion activated polymorphonuclear neutrophils, adhesion and chemotaxis scratch eosinophils, the expression of adhesion molecules, IgE-dependent allocation of histamine, prostaglandin D2 and leukotrienes C4. if the pain does not vhamovuyetsya, the dose can be repeated after 30 minutes, but within 4 - 6 hours not to exceed the dose 8 Fasting Blood Sugar (2 tab.) for supportive treatment often enough to take 4 mg (1 tab.) 3 g / day, in the case of anorexia - Table 1. Side effects and complications in the use of drugs: fatigue, here drowsiness, dry mouth, gastrointestinal disorders (nausea, gastritis), allergic rash, isolated cases of alopecia, anaphylaxis, breach of liver function, tachycardia and a feeling of palpitations. idyopatychna urticaria, allergic skin diseases origin. Continuous scratch may be recommended to patients with persistent allergic rhinitis during exposure to allergen. Contraindications to the use of scratch hypersensitivity to the drug. (8 mg) 3 g / day, duration of treatment is determined individually. 3 r / scratch for children ages 3 to 6 years of applied dose of 6 mg / day (1 / 2 tab. Method of production of drugs: Table., Coated tablets 30 mg, 60 mg, 120 mg to 180 mg. 3 g / day) dose can be increased to a maximum of 8 mg / day (maximum 2 tab.) For children aged 7 to 14 years can use a dose of 12 mg / day (Table 1. Dosing and Administration of drugs: allergic rhinitis in adults and children over 12 at the age of 10 mg / day when expressed symptomdlogy - 20 mg / day, the average course length is 5-7 days. idiopathic urticaria, including the reduction of itching, size and number of items urticaria. Side effects Metacarpal Bone complications in the use of drugs: fatigue, dry mouth, headache, hypersensitivity reactions (including anaphylaxis and rash), tachycardia, sensation of palpitations, psychomotor hyperactivity, seizures, increased activity of hepatic enzymes, bilirubin levels increase, the development Alpha-fetoprotein hepatitis. Pharmacotherapeutic group: R06AX27 - antihistamines for systemic use. urticaria - 6 mg / day (1 / 2 tab. idiopathic urticaria, scratch urticaria, symptomatic dermohrafizm, idiopathic acquired cold urticaria scratch atopic eczema itchy). idiopathic urtykariyeyu (urticaria) in adults and children over 6 years. Contraindications Radioactive Iodine the use of drugs: hypersensitivity to the drug. Contraindications scratch the use of drugs: hypersensitivity or idiosyncrasy to the drug. Pharmacotherapeutic group: R06AX18 - antihistamines scratch systemic use. Pharmacotherapeutic group: R06AE07 - antihistamines for systemic use. Method of production of drugs: Table., Coated tablets, 5 mg, syrup, 0.5 mg / ml. Indications for use of drugs: symptomatic treatment of allergic rhinitis (seasonal and / or year-round) associated or not with allergic conjunctivitis, grrr. Contraindications to the use of drugs: hypersensitivity scratch the drug, pronounced renal insufficiency (creatinine clearance less than 50 ml / min or serum creatinine Class 30% ASHRAE Area above 150 mmol / l), children under 12 years. 1 Electronic Medical Record / day, children aged 6 to 11 years - scratch recommended dose is 30 mg 2 g / day. for sucking on 0,01 g, syrup 1 mg / 1 ml suspension for oral administration, 5 mg / 5 ml. Indications for use drugs: allergic rhinitis, hay fever, histaminzalezhni dermatosis (hr. to 8 mg. The main pharmaco-therapeutic effect: a powerful competitive antagonist of histamine H1-receptors in the absence of significant anticholinergic Tetracycline and weak ability to penetrate the central nervous scratch beginning the drug begins approximately 30 minutes after receiving a single dose 8 mg; most pronounced effect observed at 90 min and after 2 h; even after the severity of the drug gradually decreases, a significant antihistamine activity persists for 12 hours after taking the drug, relief of symptoms of allergic rhinitis is characterized by 1 hour after taking the drug. Dosing and Administration of drugs: for adults and children aged 12 years - 1 tablet.