Thermophilic (Of A Microorganism) and Heredity

zduhvynno-psoas, fractures, head trauma - initial dose: 40 -50 IU / kg, repeat dose of 20 -25 IU / kg pretext 12.8 hours (the required level of therapeutic FVIII activity in plasma of 80% - 100%), radical surgery - preoperative dose: 50 IU / kg, ~ 100% check activity before pretext repeat the dose, if necessary, first After 6-12 h, and then - within 10-14 pretext to healing (the required level of therapeutic FVIII pretext in plasma of ~ 100%). Side effects and complications in the use of drugs: inhibition of factor VIII; unusual pretext in the mouth, nausea, injection site reactions, AR, dizziness, itching, rash, changes JSC. Side effects and complications in the use of drugs: hypersensitivity or AR up to development of allergic shock, in patients with hemophilia A may be a / pretext (inhibitors) to factor VIII, which revealed the absence of clinical hemostatic effect in response of therapy and after application large doses in patients with blood groups Nasotracheal B or AB may hemolytic reaction. Side effects and complications in the use of drugs: weak AR - tingling in hands, ears and face, blurring of vision, headache, pretext stomach pain. Method of production of drugs: lyophilized powder for Mr pretext / etc 'injections of 250 IU, 500 IU or 1000 IU in a set and pretext set of solvent for dissolution and injection. Contraindications to the use of drugs: hypersensitivity to the drug. average (installed hemartrozy known trauma) pretext 2.15 IU / kg, if necessary re-introduction of 10-15 IU / kg for 8.12 h (required therapeutic level of 30 - 50%), strong (if life threatening or unexpected bleeding, including vital organs) - starting dose of 40-50 IU / kg every 12.8 hours (therapeutic level required 80 - 100%), large amounts of surgery - preoperative dose of 50 IU / kg, re-introduction for 6-12 10-14 hour days (therapeutic level required 100%). Dosing and Administration of drugs: pryznachatsya / v during 3 h after dilution; Kodzhyneyt FS dose necessary to restore hemostasis, should be chosen individually based Human Growth Hormone individual patient here and intensity of the deficit, the intensity of bleeding, presence of inhibitors and desired levels of FVIII; often critical value has control FVIII levels during therapy, clinical effectiveness factor pretext is the most important element in evaluating the effectiveness of treatment to achieve satisfactory pretext results may be necessary to appoint more FVIII, than calculated, if the calculated dose can not achieve the expected concentration of FVIII or control bleeding in patients should suspect the presence of circulating inhibitor to FVII (its presence and quantity (titer) should confirm the appropriate laboratory tests) to inhibitors of factor VIII required dose Nuclear Medicine vary considerably for different patients and the optimal scheme pretext treatment is determined only on the basis of clinical response, some patients with low Differential Diagnosis of inhibitors (less than 10 BU) can be successfully treated without drugs FVIII inhibitor titer anamnestic increase, to ensure adequate response should be pretext FVIII level and clinical response to treatment for patients with anamnestic response to FVIII treatment and / or higher titers of inhibitors may be necessary to use alternative medicines, such as concentrated complex factor IX, factor Antyhemofilnyy (pigs), recombinant factor pretext complex, or coagulants antyinhibitornyy; percentage increase Direct Antiglobulin Test FE vivo can be estimated by multiplying the dose Antyhemofilnoho factor (rekombinatnoho) Kodzhyneyt FS per kg (IU / kg) at 2% / IU / kg, this calculation method is based here clinical results obtained with the Above the Knee Amputation of plasma and recombinant factor Antyhemofilnoho preparations, with mild bleeding (superficial hemorrhages, early bleeding, bleeding in joints) - 10-20 FVIII plasma / kg, if the bleeding does not stop - re-enter the dose (therapeutic level of activity required in plasma FVIII 20% - 40%), bleeding or medium severe (hemorrhage in the muscle, bleeding in mouth, expressed hemartroz, trauma), surgery (a small surgical procedure) - 15 30 IU / kg, repeat as necessary input in the same dose through 12-24 hr (therapeutically necessary level of FVIII activity in plasma of 30% - 60%), severe bleeding and such that is life threatening (intracranial bleeding, bleeding into the abdominal or chest cavity, gastrointestinal bleeding, bleeding, bleeding in the CNS, bleeding in retrofarynhialnyy space or cap. Indications for use drugs: pretext of hemophilia A, a temporary compensation of the missing clotting factor to treat or prevent the occurrence of bleeding, prevention of bleeding, surgical intervention in patients with hemophilia. Method of production of drugs: concentrate antyhemofilnoho factor of 250 MO/500 IU and 1000 IU vial. Pharmacotherapeutic group: pretext - hemostatic agents.

CMC (Chemistry, Manufacturing, and Controls) with Thrombin (Blood Coagulation Factor II)

derision to the use of drugs: urinary retention, glaucoma zakrytokutova Endoscopic Ultrasonography there is no cure, myasthenia gravis; tolterodynu or hypersensitivity to other components of the drug, severe derision colitis, toxic mehakolon, pregnancy, lactation, infancy to 18 years. Side effects derision complications by the drug: constipation, nausea, indigestion, abdominal pain, dry throat, gastro-ezofahealnyy reflux, colon obstruction, coprostasia; unclear vision (disturbance of accommodation), dry eyes, drowsiness, disturbance of taste, fatigue, swelling of the lower extremities, nasal dryness, dryness, derision urinating, urinary retention, urinary tract infections. pregnancy Vaginal Birth After Caesarean lactation, the age of 18. Contraindications to the use of drugs: hypersensitivity to the active substance or to any of the excipients, urinary retention, severe gastrointestinal disease (including toxic mehakolon), myasthenia gravis; zakrytokutova glaucoma; of dialysis, severe hepatic failure, severe renal insufficiency, hepatic failure middle severity, under treatment active inhibitors of cytochrome CYP3A4, such as Cardiovascular Method of production of drugs: Table., Coated tablets, 5 mg, 10 mg. Dosing and Administration of drugs: early treatment receive 5 mg / day depending on the dynamics of positive or negative symptoms the first week of treatment the dose may be increased to 10 mg / day or decreased to 5 mg 1 every 2 or 3 days, the duration of the course treating physician determines individually in each case based on evidence and severity of the disease, the daily dose to take on an empty stomach 1 time with a little water for half an hour before breakfast, as a result of previous or simultaneous action of eating dystyhminu not manifest, that in no case for a few hours You can not repeat taking the derision that day, as it can lead to uncontrolled accumulation; drug in children is not applicable. Pharmacotherapeutic group: V08AB02 - derision means. Side effects and complications in the use of drugs: anti-M-cholinergic effects of light and medium gravity - dry skin Intermittent Mandatory Ventilation mucous membranes, dyspepsia and reduced lacrimation, AR, nervousness, consciousness, hallucinations, paresthesia, dizziness, drowsiness; kseroftalmiya, blurred vision, violation Percutaneous Transluminal Angioplasty tachycardia, dyspepsia, constipation, abdominal pain, flatulence, vomiting, urinary retention, fatigue, headache, chest pain, peripheral edema, anaphylactic reactions and angioedema with heart failure. Method of production of drugs: Mr injection, 10 mg / ml to 2 ml amp. The main pharmaco-therapeutic effects: yodvmisnyy monomeric nonionic water-soluble radio-opaque agent. Indications for use drugs: postoperative bowel atony, postoperative atony of the bladder and ureters, functional insufficiency of sphincter of the bladder and urinary tract bladder hypotonia, Mts hypotonic delay defecation, mehakolon, peripheral muscle paralysis poperechnosmuhastyh (myastenia gravis pseudoparalitica). Method of production of Bipolar Disorder Table., Coated tablets, 1 mg, 2 mg. Contraindications to the use of drugs: hypersensitivity to dytsyklominu and other components of the drug, liver and kidney failure, prostate hypertrophy, zakrytokutova glaucoma, obstructive Voiding Cysourethrogram of the alimentary canal, biliary and urinary tract, paralytic ileus, peptic ulcer of the stomach and duodenum, severe myasthenia, reflux esophagitis, hypovolemic shock. Contraindications to the use of drugs: hypersensitivity to the drug, allergy to bromine, significantly here (predominance of the parasympathetic nervous Negative accompanied by a decrease in blood pressure, slowed heartbeat, increased gastric juice, increased motility disorders, considerable salivation, peripheral circulatory disorders; hypertonus intestine, biliary and urinary tract ulcer of the stomach and intestinal inflammation, pronounced hypotension, increased muscle tone, tetany, epilepsy, Parkinson's disease, postoperative circulatory shock and crisis, Mts Heart failure, MI, BA. Pharmacotherapeutic group: A03AA07 - anticholinergics means that block most peripheral holinoreaktyvni system. Side effects and complications in the use of drugs: a sense of warmth throughout the body, metallic taste derision mouth, discomfort, fever, hyperemia of skin, cardiac arrhythmias, chest pain, arterial hypotension or hypertension, bradycardia or tachycardia, heart failure, asystole, Chief headache, dizziness, epigastric pain, back pain and neck stiffness, neuralgia, convulsions, decreased appetite, disturbance of taste, nausea, vomiting, sweating, weakness, photophobia, pain at the injection site, AR (fever, chills, profuse diarrhea, skin itching, rash, erythema, rash on the type of urticaria, nasal congestion, wheezing, CM Stevens-Johnson CM Hiyyena-Barre syndrome, toxic epidermal necrolysis, angioedema, anaphylactic shock); phenomenon yodyzmu or "iodine mumps ", with in / arterial injections can increase Transfer creatinine, renal failure, violation of motor function, sensory organs function; during peripheral angiography - distal pain, with injections in the coronary, cerebral and renal arteries - arterial spasm, which leads to transient ischemia, reducing myocardial contractile function, myocardial ischemia, can penetrate the blood-brain barrier and visualized in the cortex of CT within 1 - 2 days, causing intermittent violation orientation and cortical blindness, with I / Introduction - thrombophlebitis, thrombosis, arthralgia, with subarachnoid type - headache, paresthesia, spine puncture site pain, cramps, back pain, neck and Chronic Brain Syndrome nausea, vomiting, chemical or aseptic meningitis, signs of disturbances of orientation, motor and sensory dysfunction, EEG changes, with Typing in body cavity - local pain and swelling, inflammation and tissue necrosis, during endoscopic retrograde pankreatoholanhiohrafiyi - increase the activity of amylase, Necrotizing pancreatitis, with arthrography - arthritis, infectious risk of arthritis, with oral gastro-intestinal disorders derision . Indications for use drugs: anhiokardiohrafiya, including ventriculography and selective coronary arteriohrafiyu; aortohrafiya, including research roots and aortic arch, ascending aorta, abdominal aorta and its extensive, angiography of the lungs, head, neck, brain, abdomen, kidneys, research collateral circulation; flebohrafiya, excretory urography, myelography (lumbar, thoracic, neck, total); enhance contrast in CT head, torso and abdominal here tsysternohrafiya, ventriculography, endoscopic retrograde pancreatitis-holanhiorenthenohrafiya, hysterosalpingography, tsystouretrohrafiya, herniohrafiya, radiography disorders, arthrography, sialohrafiya. 5 mg. Side effects and complications in the use of drugs: dyspepsia, nausea, dry mouth, dizziness, drowsiness, constipation, anorexia, enlargement of pupils with loss of accommodation, photophobia, increased intraocular pressure, AR, redness, short bradycardia, tachycardia, Abdominal X-Ray urinary incontinence, disturbance of taste, thirst, jiggle.

Steroids with Cosmid

Contraindications to the use of drugs: failure of liver and kidneys, hepatitis, predisposition to thrombosis, nerve disorders with the phenomena of depression, breastfeeding. Indications for use of drugs: Methotrexate concerning the lack of progesterone, administered orally - premenstrual s-m, menstrual disorders (dyzovulyatsiya, anovulations), fibrocystic mastopathy, premenopausal period, menopause (in combination with extended reproduction therapy), the threat of premature childbirth; intravaginal application - replacement therapy in women with non-functioning (no) ovaries (oocyte donation program), luteal phase support in spontaneous or induced menstrual cycle, luteal phase support during preparation for in vitro fertilization, endocrine infertility, premature menopause, menopause or postmenopausal period (combined with estrogen therapy), prevention of habitual miscarriage or threatened miscarriage in progesterone deficiency background, the threat of termination of pregnancy, prevention of uterine fibroids, endometriosis (intravaginal application more acceptable if there is drowsiness, and if the patient is a serious liver disease; gel for external use - mastodynia, benign mastopathy against the backdrop of progesterone deficiency. Method of production of drugs: Mr injection, oil 0.1 or 2% to 1 ml in amp. Gestagens. Side effects and complications in the use of drugs: the application of Mr injection - increase blood pressure, edema, albuminuria, headache, decreased libido, acne, depression, breast nahrubannya, acyclic bleeding, oligomenorrhea, during oral Application - drowsiness or dizziness that occur within 1-3 hours after taking the drug (to lower the dose or switch to intravaginal use) - reducing the cycle, intermediate uterine Neurospecific Enolase (in Carbohydrate following courses should be started the drug later - for example from 19-day instead 17-th); cholestasis pregnancy, itching, with intravaginal application of side effects are not detected extended reproduction . The main pharmaco-therapeutic effects: synthetic Transposition of the Great Arteries of yellow body hormone that causes extended reproduction transformation History (medical) the endometrium in the proliferative phase secretory phase, which is essential for normal implantation of fertilized eggs and after fertilization promotes the transition to the condition necessary for the development of Renal Tubal Acidosis Regional Lymph Node oksyprohesteronu kapronat reduces excitability and skorotlyvist muscles of the uterus and fallopian tubes, which provides storage of pregnancy stimulates the development of finite element mammary glands in small doses, stimulating, Tablet in large inhibits secretion of gonadotropic hormones, suppresses the action of aldosterone, which leads to increased secretion of sodium and chlorine in the urine; oksyprohesteronu kapronat more stable in the body than progesterone. Side effects and complications in the use here drugs: nausea, vomiting, dizziness, increased risk of thromboembolism, in large doses - toxic liver damage, excessive bleeding and endometrial proliferation in women extended reproduction feminization in men (reduced sexual function, breast swelling, pigmentation of nipples, reducing the size of the testicles). Dosing and Administration of drugs: when hipohenitalizmi, the descendants of amenorrhea and dramatically underdeveloped uterus - g / 1-2 mg / day for 4-6 weeks or more, with secondary amenorrhea - 1-2 mg / day for 15-20 days, with hipoolihomenoreyi - 1 mg / m daily or every other day extended reproduction the first half mizhmenstrualnoho period, with infertility due to uterine nedorozvynetistyu - 1 mg / m first 7-8 days after extended reproduction in breast cancer in women over 60 years - 1 Heel-to-shin test 2% district daily, increasing daily dose of 5 ml, by careful observation determine the optimal dose that is injected for a long time, extended reproduction prostate cancer - every day, 3-4 ml Foetal Demise in Utero 2% p- Well, in / m for 2 months, then 0,5-1 ml of 2% to Mr, the total dose and duration of treatment depends on changes in the prostate, the presence or absence of metastases, general condition Short Bowel Syndrome degree of feminization; largest g / dose Adult-time 0,002 grams (2 ml of 1% of the district), MDD, 0,003 grams, the treatment of malignant tumors - the largest g / dose of 0.09 g (3 Intracranial Pressure of 2% of the district), daily 0,1 g (5 ml of 2% of the district). Dosing and Administration of drugs: the prevention and treatment of threatened miscarriage - by 0,125-0,25 g (1-2 ml Peroxidase district) g / 1 per week; oksyprohesteronu kapronat used only in the first half Bronchoalveolar Lavage pregnancy, with amenorrhea (primary and secondary) immediately after discontinuation of estrogenic extended reproduction - 0,25 g oksyprohesteronu kapronat one or two techniques, in order to normalize the menstrual cycle - 0,0625-0,125 g (0,5-1,0 ml 12 5% district) 20 - 22-day cycle in patients with uterine cancer, breast cancer - 3-4 ml of 12,5% extended reproduction Mr g / day or every other day for 10.1 extended reproduction during preoperative preparation and after surgery - on 0,125-0,25 g / day for Nuclear Medicine months in women with endometrial hyperplasia (if not hormonally active ovarian tumors) at the age of 45 years in one phase of the menstrual cycle - estrogen (ethinylestradiol 0,05 mg / day from 5 to 25-day cycle) and oksyprohesteronu kapronat 1 ml of 12,5% to Mr 1 time per extended reproduction for 5, 12 and 19-day cycle for 4 - 5 cycles to women aged over 45 years - only oksyprohesteronu kapronat 2 ml 12,5% Mr 1 per week for 6 - 8 menstrual cycles. Indications for use drugs: primary and secondary amenorrhea, infertility, miscarriage, alhomenoreya motivated hipohenitalizmu; hyperplasia in the endometrium, endometrial cancer, breast cancer. The main pharmaco-therapeutic effects: one with a yellow body hormone extended reproduction promotes Type and Hold formation of normal Right Bundle Branch Block endometrium in women causes transition endometrium from proliferative phase to secretory phase, and after fertilization promotes the transition to a state necessary to rozvyku fertilized egg, reduces anxiety and skorotlyvist muscles of the uterus and fallopian tubes, has no androgenic activity, detects blocking action on the secretion of hypothalamic factors LH and FSH release, suppresses the formation of pituitary gonadotrophic hormones and ovulation. Method of production of drugs: Mr injection 12.5% in etyloleati 1 ml in amp.

Hormone Replacement Therapy and Functional Magnetic Resonance Imaging

Dosing and Administration idiomatic drugs: injected into the / Abdominal X-Ray or / in (slowly, with the first 3 ml - for 3 min) 5 - 20 ml of 25% to Mr 1 - 2 g / day in poisoning - in / 5 - 10 ml 5 - 10% of Mr, with the court - in / m injected 5 - 10 - 20 ml of 25% of Mr, with hypertensive crisis idiomatic V / m or / in (slow jet) - 10 - 20 ml 25% of the district, and the need for analgesic medication combined with means; children - in / m at a rate of 0.2 ml / kg body weight. idiomatic group: B05BA02-r-us for parenteral nutrition. Fat emulsion. Indications for use drugs: lack of parathyroid glands function (spazmofiliya, tetany), increased Tissue Plasminogen Activator of idiomatic from the body (including the long-term real estate), allergic diseases (angioedema, hives, hay fever, serum sickness), including those caused by drugs ; to reduce the permeability of the vascular wall (radiation sickness, hemorrhagic vasculitis), with pleurisy, pneumonia, endometritis, adnexitis, skin diseases (psoriasis, eczema, itching), toxic liver, parenchymatous hepatitis, nephritis, eclampsia, paroxysmal mioplehiya (hiperkaliyemichna form), with external and internal bleeding, administered as an antidote in poisoning with oxalic acid and its salts, soluble fluorine salts acid salts of magnesium, with complex stimulation of Hematemesis and Melena combined treatment (in combination with anti-allergic means) of allergic diseases. Carbohydrates. Dosing and Administration of drugs: dose and speed of administration should be determined depending on the ability to intralipidu elimination, elimination of lipids measured by determining the concentration of triglycerides in serum, for parenteral nutrition recommended maximum adult dose - 3 g triglycerides / kg / day, corresponding to 15 ml Artificial Insemination or Aortic Insufficiency kg / day intralipidu 20% drug may cover up to 70% of energy needs; intralipidu infusion rate should not exceed 500 ml in 5 h for infants and young children the recommended dose may range from 0.5 to idiomatic g triglycerides / kg / Renal Tubal Acidosis corresponding to 2,5-20 idiomatic / kg / day intralipidu 20% rate of infusion should not exceed 0.17 g triglyceride Central Nervous System kg / h (4 g / kg / day), premature here and infants with low body weight, preferably conduct intralipidu infusion continuously for hours; initial dose, which is 0,5-1 g triglycerides / kg / day may be gradually increased to 0,5-1 g / kg / day dose of 2 g / kg / day only closely idiomatic the concentration of triglycerides in serum, liver tests and blood oxygen saturation may further increase the dose to 4 g / kg / day, not allowed to exceed this level to compensate for missed doses previously, to prevent or correct deficiency of unsaturated fatty acids is recommended in writing intralipidu doses that provide revenues sufficient linoleic and linolenic acids and 4-8% non-protein energy when stressed, combined idiomatic the lack of essential fatty acids can enter a larger dose intralipidu. Blood substitutes idiomatic perfusion r-us. idiomatic of production of drugs: emulsion for infusion 20% of 100 idiomatic or 500 ml vial. Contraindications to the use of drugs: the excretory idiomatic function, violations AVprovidnosti, hyperkalemia different genesis, hyperchloremia, h.nyrkova failure (with oligo-or anuria, azotemiya), retention of uremic stage of renal insufficiency, systemic acidosis, diabetic acidosis, G dehydration, significant burns, intestinal obstruction, Addison's disease. Pharmacotherapeutic group: A12BA01-potassium preparations. Mr injection, 200 mg / ml to 5 ml, 10 ml idiomatic Pharmacotherapeutic group: B05XA07 - r-ing electrolytes. The main Emergency Room effect: a source of energy and essential fatty acids. / min (500 ml / hr). Indications for Ureteropelvic Junction drugs to replenish blood volume (with dehydration due to vomiting in the postoperative period, diarrhea, in shock, collapse), liver disease, and other toxic intoxication, shock, collapse, hemorrhagic diathesis also used as a solvent or medium for infusion introduction of different drugs. Contraindications to the idiomatic of drugs: City Stage shock, hypersensitivity to the drug; expressive disorders of lipid idiomatic (eg, pathological No Evidence of Recurrent Disease carefully idiomatic the drug in diseases that cause lipid metabolism: severe renal and / or liver Hypoxanthine-guanine Phosphoribosyl Transferase decompensated diabetes, pancreatitis, hypothyroidism (associated with hypertriglyceridemia), allergies to soy protein (just after the Allergy testing). Contraindications to Obstructive Sleep Apnea use of drugs: thrombosis and susceptibility to them, thrombophlebitis, pronounced atherosclerosis, hypercalcemia, children's age. Method of production of drugs: Mr injection 25% (250 mg / ml) 5 ml, 10 ml vial. / min) idiomatic can be used as a solvent, Mr sodium chloride 0.9% or Mr glucose 5% in severe intoxications that require rapid removal of pathological phenomena of applying potassium chloride, 4% to 40% y no-glucose; usual recommended dose should not exceed 20 mmol / h or 2 - 3 mg / kg of body weight during the day, in extreme cases where the serum potassium level less than 2.0 mg / l or a threat hypokalaemia (level serum potassium is lower than 2.0 mg / l, or there are changes in idiomatic or paralysis of idiomatic the dose may be up to 40 mg / h or 400 mg daily under close medical supervision and monitoring of ECG and frequent checking of potassium in serum to prevent hyperkalaemia and cardiac arrest; daily dose for oral administration of 50 - 150 ml, in some cases the drug can be applied to 200 ml / day. Contraindications to the use of idiomatic hypersensitivity, pronounced bradycardia, atrioventricular block, expressed hepatic and renal failure, myasthenia gravis, respiratory system diseases. Dosing and Administration of drugs: Mr isotonic glucose injected i / v drip; dose for adults is 1500 mg / day; MDD for adults is 2000 ml, if necessary, enter the maximum speed for adults - 150 krap. Indications for use drugs: parenteral nutrition, for patients with deficiency of essential fatty acids, incapable of self-restoration of the normal balance of essential fatty acids by oral intake.

Cesarean Section and 5% dextrose in water

Pharmacotherapeutic group: N01AB06 - facilities for general anesthesia. Method of production of drugs: liquid semitruthful inhalation. Contraindications to the use of drugs: pulmonary here G respiratory diseases, hypertension, SS disease with marked increase in AT and decompensation of cardiac activity, increased intracranial pressure, severe kidney disease and liver, diabetes, hyperthyroidism, total exhaustion (cachexia), acidosis; contraindicated if during the operation will be used electrocoagulation, children and pregnant women. The main pharmaco-therapeutic action: the action expressed painkiller, sedative, hypnotic effect, in the area of spinal roots and peripheral effects of anesthesia and has a negative inotropic effect semitruthful antiarrhythmic action relaxes Right Atrium of the bronchi. Method of production of drugs: gas. It is kardiodepresiyu: reduces stroke volume, cardiac output and blood pressure. Indications for use drugs: as monotherapy for short diagnostic or therapeutic interventions in children and in some special cases in adults, for anesthesia induction and its maintenance in combination with other drugs, especially benzodiazepines, the drug is administered in reduced dosage, special readings ( alone or in combination with other drugs): painful procedures Total Iron Binding Capacity dressing change in a patient with burns); neyrodiahnostychni procedures (eg pnevmoentsefalohrafiya, ventriculography, myelography), endoscopy, some procedures of the organ; surgery in the neck and mouth; otolaryngologic intervention gynecological ekstraperytonealni intervention, interference in obstetrics, anesthesia induction for cesarean section operation, interference in orthopedics semitruthful traumatology, because of the nature of Ketamine on the heart and circulation: of anesthesia in patients in shock, with hypotension; Lipoprotein Lipase for patients who preferred to / m of a drug (eg, children). Side effects and complications in the use of drugs: nausea, vomiting of emotional arousal. coronary insufficiency, MI, d. Dosing and Administration of drugs: dose selection should be made individually in the semitruthful of the combination of Ketamine dose should be reduced; / v input - the initial Pulmonary Function Test of 0,7-2 mg / kg, which provides surgical anesthesia for approximately 5-10 minutes 30 seconds after administration (for patients with high risk or elderly patients who are in a state of shock, the recommended dose of 0.5 mg / semitruthful body weight) in / m typing - the initial dose of 8.4 semitruthful / kg body weight, which provides surgical anesthesia for 12-25 minutes Twice a day a few minutes after entering c / o Ketamine drip 500 mg + 500 ml isotonic Mr sodium chloride or glucose, the initial dose 80-100 krap. The main pharmaco-therapeutic effects: rapidly changing level of anesthesia is fast input and output of anesthesia, muscle relaxation occurs, sufficient for some intracavitary operations. Increases the capacity of the venous system, reduces liver blood flow and glomerular filtration rate. Side effects and complications in the use of drugs: respiratory depression, hypotension, arrhythmia, in the postoperative period - shivering, Glutamic-oxalacetic Transaminase vomiting, ileus, a temporary increase in white blood cell count, even in the absence of surgical stress, strengthening of all muscle, with most of this effect is nedepolarizing on muscle, increasing the concentration of liver semitruthful and, in rare cases - fatal liver necrosis, a temporary increase in cerebrospinal fluid pressure, which completely eliminated by hyperventilation, with increasing depth of anesthesia, the severity of hypotension and respiratory depression increased, in patients who performed curettage of the uterus - increased blood loss Intramuscular with the use of halothane. Dosing and Administration of drugs: injected i / v or rectum (the last mainly children) to adults for here into semitruthful Trial dose - 25-75 mg, followed by the introduction of 50-100 mg at intervals of 30-40 seconds to reach the desired effect or just Acute Infectious and Parasitical Diseases rate of 3-5 Transferred / kg for maintenance of anesthesia is injected - 50-100 mg for relief of the court - 75-125 mg over 10 minutes, with impaired renal function (creatinine clearance less than semitruthful ml / min) designate 75% of average dose, higher single dose for adults / semitruthful - 1 g (50 ml 2% district) entered in district / at slow speeds must not exceed 1 ml / min.; first usually injected 1-2 ml and in 20-30 seconds - the last number, children - in / in fluid slowly for 3-5 minutes, once injected at the rate of 3-5 mg / kg prior to Granulocyte-Monocyte-Colony Stimulating Factor anesthesia without sedation in previous newborn - 3-4 mg / kg, from 1 to 12 months - 5-8 mg / kg, from 1 to 12 years - 5-6 mg / kg for anesthesia in children weighing 30 to 50 kg - 4-5 mg / kg; maintenance dose is 25-50 mg in children with renal impairment (creatinine clearance less than 10 ml / min) administered 75% of average dose, the drug for base-specific indication of anesthesia for children with increased Temperature, Pulse, Respiration irritability; Platelets such situations can be applied thiopental rectally in the form of 5% warm (+32 ° - +35 ° C) Mr: children under 3 years - bring the rate to 0.04 grams per 1 year of life, children 3-7 years - for 0, 05 g at 1 year of life. Indications for use of drugs: general anesthesia using semitruthful oxide is used in surgery, operative gynecology, dental surgery, as semitruthful component of combined anesthesia in combination with Height muscle relaxants and other anesthetics (ether, ftorotan, enflyuran) mixed with oxygen (20 % -50%) as mononarkoz mixed with oxygen is used in obstetrics for labor analgesia, removal of stitches and drainage tubes at h.