Used in severe staphylococcal lessen streptococcal infections (sep-titsemiya, pneumonia, brain abscess, pulmonary, meningitis, peritonitis, osteomyelitis, streptococcal endocarditis); injected ka-pelno. Benzathine benzylpenicillin (bitsillin1) after intramuscular injection is absorbed very slowly; concentration in lessen blood low, the duration of drug action is dependent on dose 1-2 weeks. Side effects of vancomycin: phlebitis, hypotension, muscle aches, skin rash, pyrexia, neutropenia, renal dysfunction, ototoxic effect. If ingestion (prepara-rat is practically not absorbed in the gastrointestinal tract), vancomycin is highly effective in pseudomembranous colitis (vyzy-is called Clostridium difficile). Aminopenicillins no effect on the microorganisms that produce betalaktamazy (including penicillinase). Violates the synthesis of peptidoglycan. Effect on staphylococci, stable curves to benzylpenicillin. coli. Is used to treat syphilis, and streptococcal pharyngitis, diphtheria, for the prevention of seasonal exacerbations of rheumatism. Ampicillin worse absorbed and ingestion is more effective lessen lessen agenda of gastrointestinal tract. Amoxicillin is lessen absorbed in the intestine. 329). Vancomycin acts bactericidal, mainly on gram-positive bacteria. lessen aminopenicillins advisable to appoint, together lessen inhibitors betalakta Maze - clavulanic acid or sulbactam. Intramuscularly or intravenously Computed Tomography Angiography meningitis, septicemia, pneumonia, urinary tract infections caused by susceptible to the drug by bacteria. Drug is prescribed inside the ka-zhdye 8 h. Mild Traumatic Brain Injury mainly on lessen bacteria, including staphylococci, penicillinase producing. Penicillins low toxicity, but more often than other antibiotics, cause hypersensitivity reactions: urticaria, angioedema, possibly fever, arthralgia, time-motion kidneys, anaphylactic shock. IV generation cephalosporins act on gram-positive and Gram-tional bacteria, are effective against Pseudomonas coli and Proteus. Karboksipenitsilliny - carbenicillin here intramuscularly) and karfetsil-ling (appointed interior) are similar to the spectrum of lessen with aminopenicillins. Virtually ineffective against a pale treponema. Ineffective against most strains of staphylococcus metitsillinrezistentnyh. Effective against Clostridium difficile. One of the few antibiotics that are effective metitsillinrezistentnyh against staphylococci. Drugs in this group - meropenem and imipenem - antibiotics action spectrum. Unlike aminopenicillins act on sineg-Noyna wand. Strains of staphylococci resistant to these drugs, called metitsil-linrezistentnymi staphylococci. Preparations appointed interior; cloxacillin and oxacillin, in addition, administered parenterally. Imipenem is inactivated degidropeptidazoy kidneys, so it is prescribed together with an inhibitor of this enzyme - cilastatin; there is a combined medication tienam. Glycopeptide antibiotics - vancomycin, teikoplanin violate the synthesis of peptidoglycan. Broad-spectrum antibiotics. Ceftriaxone is different duration of action - 24 am-muscular Enter intramuscularly 1 time per day or intravenously at heavy infections (septicemia, pneumonia, meningitis, acute pyelonephritis, pelvic infections, osteomyelitis, arthritis). The first drug of this group was methicillin. lessen the same here are quite high drug concentration in the blood. Benzylpenicillin in general little toxic but can cause hyper-sensitivity reactions - urticaria, pyrexia, pain joint pain, rashes, angioedema, anaphylactic shock. In heavy cases, medication is lessen intravenously. Side effects of cephalosporins: an allergic reaction is possible nephro-toxicity, especially when using a drug generation. In this group of penicillins, isolated aminopenicillins, karboksipenitsil-Lina, ureidopenitsilliny. Ureidopenitsilliny lessen azlocillin, piperacillin - broad-spectrum antibiotics.
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