শুক্রবার, ৩ জুন, ২০১১
LCM and Acute Interstitial Nephritis
Baclofen is also effective in phantom pains. Fentanyl or talamonal can be applied to eliminating the pain of injuries. To accelerate the elimination of morphine from organism used forced diuresis or peritoneal dialysis. Analgesic effects, sufficient to for short surgical procedures, providing ketamine (ketalar), which blocks the receptors of excitatory amino acids (NMDApetseptor). Naloxone is administered intravenously or intramuscularly in subsidiary of poisoning opioid analgesics. combined with neuroleptic droperidolom (combined drug - talamonal) fentanyl is used for neyroleptanalgezii (Method of pain relief Coronary Angiography preserved consciousness during surgery). Little effect on respiration. Due to the high content of morphine omnopon applied for the same indications as morphine. When headache, migraine, neuralgia, arthralgia, myalgia, algodismenoree used paracetamol (acetaminophen, Panadol), which reduces pain due to the inhibition of cyclooxygenase in the CNS. Has a weak inflammatory Negative Stimulates the reduction of the subsidiary Apply trimeperidin myocardial infarction, malignant subsidiary trauma, as well as pain associated with spasm of smooth muscles of internal organs. To preparations containing morphine, is omnopon (Pantopon) - mixture of 5 alkaloids in subsidiary (morphine and codeine, papaverine, nartsein, thebaine). Trimeperidin contraindicated in respiratory depression. As an analgesic and antitussive used as dihydrocodeine. Tramadol appointed interior, under the skin, intramuscularly, intravenously for pain associated with malignant tumors, myocardial infarction, and trauma. Significantly more codeine is used as antitussive. When trigeminal neuralgia, which is usually accompanied by subsidiary of severe pain, are effective blockers of sodium channels of carbamazepine (tegretol, finlepsin) and phenytoin (diphenine), as well as agonist baclofen GAMKvretseptorov (providing depressant effect on the selection of mediators from primary afferents). Stimulate oretseptor (sigmaretseptor), subsidiary therefore the Wandering Atrial Pacemaker application can be dysphoria, hallucinations, tachycardia, increased blood pressure. In connection with the blockade tsretseptorov these drugs compared with morphine less dangerous with regard to drug dependence, less respiratory depression. The highest daily dose of paracetamol - 4 in case of overdose paracetamol is the possibility of severe liver damage (necrosis) because of the toxic metabolite of paracetamol - Natsetilpbenzohinonimina (at therapeutic doses of paracetamol, this metabolite is rapidly inactivated by glutathione). Used fentanyl for sedation before surgery, for pain subsidiary the postoperative period. Opioid antagonists analgesics - naloxone and naltrexone block mainly tsretseptor and to a lesser extent kretseptor and 8retseptor. Ligament heroin can cause particularly severe drug dependence. Tramadol (Tramal) has the properties of opioid analgesics (stimulates myuretseptor), and furthermore, breaks back neuronal capture of norepinephrine and serotonin, ie, activates noradrenergic and serotonergic transmission, and may enhance downstream inhibitory effects on the conduct pain impulses. In case of deep respiratory depression have resorted to artificial ventilation. Pronounced analgesic properties have nitrous oxide, which is used by inhalation for pain relief myocardial infarction in the postoperative period for labor analgesia. In contrast, morphine omnopon does not cause spasm of smooth muscles, as it contains alkaloids of isoquinoline series - papaverine and nartsein having myotropic inflammatory properties. Length of fentanyl 20-30 min. As a result, when using heroin euphoria develops faster and more pronounced than with morphine. Fentanyl (stimulates mainly tsretseptor) is 100 times more active than morphine, ie, used in doses Gastroesophageal Reflux Disease are 100 times less than morphine. On analgesic effect of morphine is inferior. However, the pharmacological properties of these drugs are similar to morphine. The drug has about 2 pm If necessary, naloxone administered repeatedly. On the chemical structure of morphine differ trimeperidin and fentanyl - Derivatives phenylpiperidine. When the pain associated with spasm of smooth muscles, such as kidney and liver colic, omnopon has an advantage over morphine. Codeine may be effective in acute infectious diarrhea. In individuals with drug addiction to opioids, Nuclear Magnetic Resoance drugs can cause withdrawal symptoms. Droperidol: potentiates the analgesic effect of fentanyl, eliminates the patients anxiety, fear, anxiety, promoting subsidiary development of indifference to surroundings, including those for surgery (state neyrolepsii). The drug was appointed interior, injected subcutaneously, intramuscularly or intravenously.
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